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Botox, Jeuveau, Dysport, Dexxify, or Xeomin? Which is the Right Neuromodulator for my wrinkles?

Welcome to White Pebble Dermatology — your trusted dermatology practice serving Columbia and Highland, Maryland, and their surrounding areas.

When it comes to addressing those bothersome wrinkles and frown lines, neuromodulators like Botox, Jeuveau, Dysport, Dexxify, and Xeomin have emerged as go-to solutions. These treatments offer a non-invasive way to temporarily reduce the appearance of facial wrinkles, providing a more youthful and refreshed look. But how do you choose the right one for you?

Botox: The Pioneer

  • Botox, also known as Botulinum Toxin Type A, is the OG (original gangster) of neuromodulators. It's been in the game for quite some time and is FDA-approved for both cosmetic and medical applications.

  • Botox works by temporarily blocking nerve signals to the muscles, reducing their activity and, subsequently, the appearance of wrinkles. Common areas for treatment include frown lines, forehead lines, and crow's feet.

Jeuveau: The New Kid on the Block

  • Jeuveau, also known as NEWTOX, is an injectable treatment utilizing botulinum toxin type A. Similar to other BTX injections, it temporarily blocks neurological signals to muscles, effectively reducing wrinkles and frown lines.

  • FDA-approved in 2019, Jeuveau has gained popularity as a cost-effective alternative to BOTOX due to its lower pricing. While the exact cost varies based on several factors, Jeuveau injections typically come at a more affordable price point than BOTOX. The manufacturer, Evolus, achieved this by focusing exclusively on cosmetic applications, making Jeuveau suitable for treating wrinkles and frown lines in cosmetic procedures.

Dysport: Speed and Spread

  • Dysport, also an FDA-approved botulinum toxin type A product, is known for its rapid onset of action. It spreads more widely than Botox, making it a suitable choice for treating larger areas.

  • This can be an advantage when targeting broader areas like forehead wrinkles. If you're looking for quicker results with a slightly different spread pattern, Dysport might be worth considering.

Dexxify: The Newcomer with Longevity

Dexxify is a newcomer in the field, gaining FDA approval in 2022.

Botox vs. Dexxify: The Duration Difference

  • The main difference between Botox and Dexxify is how long they provide results. Dexxify results last longer than Botox, typically 2 times longer than Botox and other neurotoxins.

  • Dexxify patients can expect to stay wrinkle-free for 6 months, whereas Botox tends to last for only 3-4 months.

  • The reason Dexxify can last longer is due to its unique formulation: Dexxify combines its toxin with a unique protein that lengthens the toxin’s effects. This protein is absent in Botox.

  • Since the results that Dexxify generates last longer, patients do not have to undergo as many maintenance treatment sessions to maintain their results.

  • However, it's important to note that Dexxify's dosing unit is doubled compared to all other neuromodulators such as Botox. This means that to achieve the desired results, a double amount of Dexxify needs to be injected.

Xeomin: The "Naked" Neurotoxin

  • Xeomin, another botulinum toxin type A product, is often referred to as the "naked" neurotoxin because it lacks additives.

  • This might be a consideration for those concerned about potential allergenic reactions. Xeomin is FDA-approved for cosmetic uses to treat frown lines.

Similarities and Differences Among These Popular Cosmetic Injectables

  • It's important to note that all of these neuromodulators have more similarities than differences.

  • They all effectively reduce wrinkles by temporarily relaxing targeted muscles.

  • Additionally, they are administered through minimally invasive injections and require little to no downtime.

  • The main differences lie in factors like the duration of results, spread pattern, cost, and FDA approvals for specific applications.

  • Dexxify stands out for its longer-lasting results, while Dysport is known for its quick onset and wider spread.

  • Jeuveau offers an affordable alternative, and Xeomin appeals to those seeking a "naked" neurotoxin.

So, which neuromodulator is right for you? The answer depends on factors like your treatment goals, budget, and how long you want your results to last.

Consulting with a dermatology specialist is the best way to determine the most suitable option for your unique needs.

Ready to embark on your journey to a more youthful appearance? Reach out to us at White Pebble Dermatology by calling or texting 443-535-6616, or book online at

Located conveniently in Columbia and Highland, Maryland, our experienced dermatology specialists are here to guide you through the process and help you make an informed decision.

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